Basic information Safety Supplier Related

6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE

Basic information Safety Supplier Related

6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE Basic information

Product Name:
6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE
Synonyms:
  • 6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE
  • PD 160170
  • 8-Quinolinamine, 6-[[2-(1-methylethyl)phenyl]sulfonyl]-5-nitro-
CAS:
181468-88-2
MF:
C18H17N3O4S
MW:
371.41
Product Categories:
  • Neuropeptide Y (NPY ) receptor
Mol File:
181468-88-2.mol
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6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE Chemical Properties

Boiling point:
646.6±55.0 °C(Predicted)
Density 
1.379±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 100 mM in DMSO
form 
Powder
pka
-1.16±0.12(Predicted)
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6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE Usage And Synthesis

Definition

ChEBI: 5-nitro-6-(2-propan-2-ylphenyl)sulfonyl-8-quinolinamine is a nitro compound and a member of quinolines.

Biological Activity

Potent, selective non-peptidic neuropeptide Y 1 receptor antagonist (K i = 48 nM); selective over Y 2 and Y 5 receptors (K i > 10 μ M). Antagonizes NPY-mediated inhibition of cAMP accumulation in SK-N-MC cells (IC 50 = 8.2 nM).

6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINESupplier

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6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE(181468-88-2)Related Product Information