LOE 908 HYDROCHLORIDE
LOE 908 HYDROCHLORIDE Basic information
- Product Name:
- LOE 908 HYDROCHLORIDE
- Synonyms:
-
- LOE 908 HYDROCHLORIDE
- LOE 908
- 3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
- Pinokalant
- 1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-
- CAS:
- 149759-26-2
- MF:
- C41H48N2O9
- MW:
- 712.83
- Mol File:
- 149759-26-2.mol
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LOE 908 HYDROCHLORIDE Chemical Properties
- Boiling point:
- 803.7±65.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- pka
- 5.47±0.20(Predicted)
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LOE 908 HYDROCHLORIDE Usage And Synthesis
Uses
LOE 908 Hydrochloride is a isoquinoline derivative and a cation channel blocker. LOE 908 Hydrochloride is a neuroprotective agent.
Biological Activity
Broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.
LOE 908 HYDROCHLORIDESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
Beijing HuaMeiHuLiBiological Chemical
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- 010-56205725
- waley188@sohu.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com
Career Henan Chemica Co
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- +86-0371-86658258 15093356674;
- laboratory@coreychem.com