Basic information Safety Supplier Related

Virginiamycin S1

Basic information Safety Supplier Related

Virginiamycin S1 Basic information

Product Name:
Virginiamycin S1
Synonyms:
  • Virginiamycin S1
  • Antibiotic 1754Z3B
  • N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-L-pipecoloyl-L-phenyl Gly-]
  • N-[(3-Hydroxy-2-pyridyl)carbonyl]cyclo(L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-L-2-piperidinecarbonyl-L-phenyl Gly-)
  • Staphylomycin S
  • Cebin V, Eskalin V, EskaMicin, Stafac, StephyloMycin, MikaMycin, Ostreogrycin, Patricin, PristinaMycin, StreptograMin, VernaMycin.
  • VirginiaMycin coMplex
  • Antibiotic 899, Staphylomycin S
CAS:
23152-29-6
MF:
C43H49N7O10
MW:
823.89
EINECS:
245-462-6
Product Categories:
  • antibiotic
Mol File:
23152-29-6.mol
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Virginiamycin S1 Chemical Properties

Melting point:
240-242°
alpha 
D20 -28° (c = 1 in ethanol)
storage temp. 
?20°C
solubility 
methanol: soluble5mg/mL
form 
powder
color 
white
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Safety Information

WGK Germany 
3
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Virginiamycin S1 Usage And Synthesis

Uses

Virginiamycin complex is defined as a mixture of 75% ostreogrycin A (virginamycin M1) and 25% virginiamycin S1, together with the less abundant S analogues. As the two major components have quite different solubilities, these proportions are not readily achieved or used. BioAustralis has isolated and re-combined the individual components to provide the defined components of virginiamycin complex. The composition of the complex is important as Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Uses

Virginiamycin S1 is one of a family of depsipeptide antibiotics co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A. 

Contact allergens

Like the other streptogramin, pristinamycin, virginiamycin is made of two subunits, virginiamycin S1 and virginiamycin M1. Dermatitis was quite common in people using the formerly available topical virginiamycin. Occupational dermatitis was observed in the pharmaceutical industry, in breeders, and in a surgeon who used topical virginiamycin on postoperative wounds (personal observation).

Virginiamycin S1 Supplier

ChemStrong Scientific Co.,Ltd
Tel
0755-66853366-
Email
sales@chem-strong.com
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169-
Email
kewelchemexp@yahoo.com
Alta Scientific Co., Ltd.
Tel
022-65378550- ;022-65378550-
Email
sales@altascientific.com;marketing@altascientific.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885
Email
info@efebio.com
Novachemistry
Tel
+44 (0)208 191 7890
Email
info@novachemistry.com