3,4-dihydro-3,4-dioxonaphthalene-1-sulphonic acid Chemical Properties

Density 

1.68±0.1 g/cm3(Predicted)

pka

-4.27±0.20(Predicted)

EPA Substance Registry System

1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo- (2066-93-5)

3,4-dihydro-3,4-dioxonaphthalene-1-sulphonic acid Usage And Synthesis

Uses

Doxazosin impurity 12 is a CTX-Mβ-lactamase inhibitor, with a Ki value of 0.7 mM for CTX-M[1].

Definition

ChEBI: 1,2-naphthoquinone-4-sulfonic acid is an arenesulfonic acid that is 1,2-naphthoquinone substituted at position 4 with a sulfonic acid group. Used principally as a reagent in colorimetric determinations. It has a role as a colorimetric reagent. It is an arenesulfonic acid and a naphthalenone.

References

[1] Yu Chen, et al. Molecular docking and ligand specificity in fragment-based inhibitor discovery. Nat Chem Biol. 2009 May;5(5):358-64. DOI:10.1038/nchembio.155