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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

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5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Basic information

Product Name:
5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
Synonyms:
  • 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
  • Mobocertinib succinate intermediate
CAS:
1847464-89-4
MF:
C29H35N7O5
MW:
561.64
Mol File:
1847464-89-4.mol
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5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Chemical Properties

Boiling point:
754.3±70.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
pka
9.00±0.28(Predicted)
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5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Usage And Synthesis

Description

The IUPAC Name of 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester is isopropyl 2-((4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate. This compound is an intermediate of Mobocertinib succinate which is an orally active and irreversible EGFR/HER2 inhibitor.

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl esterSupplier

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