Basic information Safety Supplier Related

Bizelesin

Basic information Safety Supplier Related

Bizelesin Basic information

Product Name:
Bizelesin
Synonyms:
  • 1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea
  • NSC-615291
  • U-77779
  • (8S,8'S)-6,6'-[Carbonylbis(iMino-1H- indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe
  • N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea
  • Bizelesin
  • 1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea
  • Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-
CAS:
129655-21-6
MF:
C43H36Cl2N8O5
MW:
815.7
Product Categories:
  • Chiral Reagents
  • Indole Derivatives
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
129655-21-6.mol
More
Less

Bizelesin Chemical Properties

Density 
1.604±0.06 g/cm3(Predicted)
pka
10.06±0.40(Predicted)
form 
Solid
color 
Off-white to yellow
More
Less

Bizelesin Usage And Synthesis

Uses

As members of the cyclopropylpyrroloindole family, Adozelesin and Bizelesin cause genomic DNA lesions by alkylating DNA. Adozelesin induces single-strand DNA lesions, whereas Bizelesin induces both si ngle-strand lesions and double-strand DNA cross-links. liferation by different pathways (i.e., Adozelesin induced apoptosis, and Bizelesin induced senescence).

BizelesinSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
LGM Pharma
Tel
1-(800)-881-8210
Email
inquiries@lgmpharma.com
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Email
info@yuhaochemical.com
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266