(+/-)-N-3-Benzylnirvanol
(+/-)-N-3-Benzylnirvanol Basic information
- Product Name:
- (+/-)-N-3-Benzylnirvanol
- Synonyms:
-
- (+/-)-N-3-Benzylnirvanol
- 3-Benzyl-5-ethyl-5-phenyl-hydantoi
- 5-Ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione
- 3-Benzyl-5-ethyl-5-phenyl-hydantoin
- 5-ETHYL-5-PHENYL-3-BENZYL-2,4-IMIDAZOLIDINEDIONE
- 2,4-Imidazolidinedione, 5-ethyl-5-phenyl-3-(phenylmethyl)-
- CAS:
- 93879-40-4
- MF:
- C18H18N2O2
- MW:
- 294.35
- Product Categories:
-
- All Inhibitors
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 93879-40-4.mol
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(+/-)-N-3-Benzylnirvanol Chemical Properties
- Melting point:
- 134-136°C
- Density
- 1.190±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 8.02±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
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(+/-)-N-3-Benzylnirvanol Usage And Synthesis
Description
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 μM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of cholesterol in mice.
Chemical Properties
White Solid
Uses
It is a potent and selective human CYP2C19 inhibitor
(+/-)-N-3-BenzylnirvanolSupplier
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