Basic information Safety Supplier Related

(+/-)-N-3-Benzylnirvanol

Basic information Safety Supplier Related

(+/-)-N-3-Benzylnirvanol Basic information

Product Name:
(+/-)-N-3-Benzylnirvanol
Synonyms:
  • (+/-)-N-3-Benzylnirvanol
  • 3-Benzyl-5-ethyl-5-phenyl-hydantoi
  • 5-Ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione
  • 3-Benzyl-5-ethyl-5-phenyl-hydantoin
  • 5-ETHYL-5-PHENYL-3-BENZYL-2,4-IMIDAZOLIDINEDIONE
  • 2,4-Imidazolidinedione, 5-ethyl-5-phenyl-3-(phenylmethyl)-
CAS:
93879-40-4
MF:
C18H18N2O2
MW:
294.35
Product Categories:
  • All Inhibitors
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
93879-40-4.mol
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(+/-)-N-3-Benzylnirvanol Chemical Properties

Melting point:
134-136°C
Density 
1.190±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
8.02±0.70(Predicted)
form 
Solid
color 
White to Off-White
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(+/-)-N-3-Benzylnirvanol Usage And Synthesis

Description

(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 μM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of cholesterol in mice.

Chemical Properties

White Solid

Uses

It is a potent and selective human CYP2C19 inhibitor

(+/-)-N-3-BenzylnirvanolSupplier

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