6-Bromo-2-nitro-pyridin-3-ol Chemical Properties

Boiling point:

413.0±40.0 °C(Predicted)

Density 

2.006±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

pka

-1.31±0.10(Predicted)

Appearance

Light yellow to yellow Solid

InChI

InChI=1S/C5H3BrN2O3/c6-4-2-1-3(9)5(7-4)8(10)11/h1-2,9H

InChIKey

GSGNTVQLHGOEMB-UHFFFAOYSA-N

SMILES

C1([N+]([O-])=O)=NC(Br)=CC=C1O

Safety Information

HS Code 

2933399990

6-Bromo-2-nitro-pyridin-3-ol Usage And Synthesis

Uses

6-?Bromo-?2-?nitropyridin-?3-?ol acts as a reagent for the synthesis of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents. Also, functions as a reagent for the preparation of α-styrylpyridines via palladium-catalyzed coupling of N-tosylhydrazones with halopyridines, and their antitumor activity.

References

[1] Patent: WO2006/81178, 2006, A2. Location in patent: Page/Page column 22
[2] Patent: WO2006/81179, 2006, A1. Location in patent: Page/Page column 23
[3] Patent: WO2006/81264, 2006, A1. Location in patent: Page/Page column 24-25
[4] Patent: WO2006/81289, 2006, A2. Location in patent: Page/Page column 22
[5] Patent: WO2006/81182, 2006, A2. Location in patent: Page/Page column 22-23

6-Bromo-2-nitro-pyridin-3-ol(443956-08-9)Related Product Information

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• 3-Hydroxy-2-nitropyridine
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• 2-BROMO-6-NITROPYRIDINE
• 6-Bromo-2-nitro-pyridin-3-ol
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