ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Arginine derivatives > FA-ALA-ARG-OH
FA-ALA-ARG-OH
FA-ALA-ARG-OH Basic information
- Product Name:
- FA-ALA-ARG-OH
- Synonyms:
-
- furylacryloylalanylarginine
- 3-(2-FURYL)ACRYLOYL-ALA-ARG-OH
- 3-(2-FURYL)-ACRYLOYL-ALA-ARG SALT
- FA-ALA-ARG-OH
- FA-AR-OH
- L-Arginine, N-[3-(2-furanyl)-1-oxo-2-propen-1-yl]-L-alanyl-
- N-[3-(2-Furanyl)-1-oxo-2-propen-1-yl]-L-alanyl-L-arginine
- (2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]propanoyl]amino]pentanoicaci
- CAS:
- 76079-06-6
- MF:
- C16H23N5O5
- MW:
- 365.38
- Mol File:
- 76079-06-6.mol
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FA-ALA-ARG-OH Chemical Properties
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 3.34±0.10(Predicted)
- Sequence
- {FA}-Ala-Arg
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FA-ALA-ARG-OH Usage And Synthesis
Uses
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1].
References
[1] Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149(10):4821-8. DOI:10.1210/en.2008-0145
FA-ALA-ARG-OHSupplier
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