ANTI-CDK8
ANTI-CDK8 Basic information
- Product Name:
- ANTI-CDK8
- Synonyms:
-
- CDK8 (AB-1) POLYCLONAL ANTIBODY
- Anti-Cdk8 antibody produced in rabbit
- Anti-CDK8 (421-435) antibody produced in rabbit
- Monoclonal Anti-CDK8 antibody produced in mouse
- ANTI-CDK8 (352-360) RABBIT PAB
- ANTI-CDK8
- ANTI-CYCLIN-DEPENDENT KINASE 8 (CDK 8)
- ANTI-CDK8 (352-360), HUMAN
- MW:
- 0
- Mol File:
- Mol File
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ANTI-CDK8 Chemical Properties
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
MSDS
- Language:English Provider:SigmaAldrich
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ANTI-CDK8 Usage And Synthesis
Uses
Anti-CDK8 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
General Description
Anti-CDK8 Antibody detects endogenous levels of total CDK8 protein.
Biological Activity
CDK8 is a regulator of transcription in a multisubunit complex with TFIIH and TEF-β. It exerts positive and negative effects on transcription and is involved signaling th at controls nutrient sensing and cell differentiation. CDK8 phosphorylates the regulatory serine residue of STAT1 and mediates JAK-STAT1 signaling.