Basic information Safety Supplier Related

panepoxydone

Basic information Safety Supplier Related

panepoxydone Basic information

Product Name:
panepoxydone
Synonyms:
  • (1S,6S)-5β-Hydroxy-3-[(R)-1-hydroxy-3-methyl-2-butenyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
  • (1β,6β)-3-[(1R)-1-Hydroxy-3-methyl-2-butenyl]-5β-hydroxy-7-oxabicyclo[4.1.0]hepta-3-ene-2-one
  • (1S,5R,6S)-5-Hydroxy-3-[(1S)-1-hydroxy-3-methyl-2-buten-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
  • 7-Oxabicyclo[4.1.0]hept-3-en-2-one, 5-hydroxy-3-[(1S)-1-hydroxy-3-methyl-2-buten-1-yl]-, (1S,5R,6S)-
  • Panepoxydone from Lentinus conatus, >=95% (HPLC)
CAS:
31298-54-1
MF:
C11H14O4
MW:
210.23
Mol File:
31298-54-1.mol
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panepoxydone Chemical Properties

Boiling point:
437.9±45.0 °C(Predicted)
Density 
1.338±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble10mg/mL
form 
powder
pka
12.67±0.40(Predicted)
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Safety Information

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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panepoxydone Usage And Synthesis

Biochem/physiol Actions

Panepoxydone is a fungal metabolite that inhibits NF-κB transcription factor by preventing IκB phosphorylation, thus inhibiting the release of NF-κB from the IκB : NF-κB complex and its translocation into the nucleus. Panepoxydone also has antimalarial, cytotoxic activities and anti-parasitic activity against Trypanosoma cruzi.

panepoxydoneSupplier

Sigma-Aldrich
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