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(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

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(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Basic information

Product Name:
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
Synonyms:
  • Crizotinib Impurity 5
  • 100968
  • benzeneMethanol, 2,6-dichloro-3-fluoro-α-Methyl-, (alphaR)-
  • BenzeneMethanol,2,6-dichloro-3-fluoro-a-Methyl-, (aR)-
  • Crizotinib InterMediate
  • Benzenemethanol, 2,6-dichloro-3-fluoro-α-methyl-, (αR)-
  • (R)-2,6-Dichloro-3-fluoro-alpha-methylbenzyl Alcohol
  • (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
CAS:
330156-50-8
MF:
C8H7Cl2FO
MW:
209.04
EINECS:
808-063-3
Product Categories:
  • Chiral Compounds
Mol File:
330156-50-8.mol
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(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Chemical Properties

Melting point:
41.0 to 45.0 °C
Boiling point:
261 °C
Density 
1.406
Flash point:
112 °C
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
powder to crystal
pka
13.30±0.20(Predicted)
color 
White to Almost white
InChIKey
JAOYKRSASYNDGH-SCSAIBSYSA-N
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Safety Information

HS Code 
2906.29.6000
HazardClass 
IRRITANT
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(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Usage And Synthesis

Description

(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an alcohol derivative and can be used as a pharmaceutical intermediate.

Uses

(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is used in the synthesis of anti-tumor molecular targeted drug of Crizotinib (C785000).

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