N-Boc-cadaverine Chemical Properties

Boiling point:

309.2±25.0 °C(Predicted)

Density 

0.972 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.460

Flash point:

109 °C

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

pka

12.91±0.46(Predicted)

form 

Oil

color 

Yellow

BRN 

3603658

InChIKey

DPLOGSUBQDREOU-UHFFFAOYSA-N

CAS DataBase Reference

51644-96-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2735 8/PG 3

WGK Germany 

3

F 

10-34

HazardClass 

8

PackingGroup 

Ⅲ

HS Code 

2924190090

MSDS

• Language:English Provider:SigmaAldrich

N-Boc-cadaverine Usage And Synthesis

Description

tert-Butyl (5-aminopentyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-Butyl (5-aminopentyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Some of the reported applications of N-Boc-cadaverine include:

• Synthesis of of a supermacrocycle that self-assemble to form organic nanotubes.
• Preparation of water-soluble unsymmetrical sulforhodamine fluorophores from monobrominated sulfoxanthene dye.
• Synthesis of functionalized porphyrins as biocompatible carrier system for photodynamic therapy (PDT).

Uses

N-Boc-cadaverine is an intermediate in the synthesis of derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.

N-Boc-cadaverine(51644-96-3)Related Product Information

• 4-(tert-ButoxycarbonylaMino)-1-butanol
• N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate
• N,N'-Disuccinimidyl carbonate
• 1,3-DI-BOC-2-METHYLISOTHIOUREA
• Carbamic acid, (4-amino-2-butynyl)-, 1,1-dimethylethyl ester (9CI)
• Carbamic acid, (tetrahydro-4-oxo-2H-pyran-3-yl)-, 1,1-dimethylethyl ester (9CI)
• tert-butyl N-(4,4-dimethyl-3-oxopentyl)-N-methylcarbamate
• tert-butyl N-(4-hydroxy-3-methylcyclohexyl)carbamate
• tert-butyl N-(5-aminonaphthalen-1-yl)carbamate
• tert-butyl N-(5-{[(tert-butoxy)carbonyl]amino}-3-oxopentyl)c arbamate
• N,N'-Di-Boc-L-lysine hydroxysuccinimide ester
• Boc-Lys-OH
• Ne-Boc-L-lysine tert-butyl ester hydrochloride
• H-Lys(Boc)-OH
• BOC-HOARG-OH
• BOC-LYS(TFA)-OH
• N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine
• BOC-LYS(BOC)-OH DCHA