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H-Lys(Boc)-OH

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H-Lys(Boc)-OH Basic information

Product Name:
H-Lys(Boc)-OH
Synonyms:
  • Lys(Boc)-OH
  • (S)-2-AMino-6-((tert-butoxycarbonyl)aMino)hexanoic acid
  • L-Lysine,N6-[(1,1-diMethylethoxy)carbonyl]-
  • H-Lys(Boc)-OH >=95%
  • Nε-Boc-L-Lysine≥ 98% (HPLC)
  • Ne-Boc-L-lysine Nε-Boc-L-lysine N-epsilon-tert-Butoxycarbonyl-L-lysine
  • Nepsilon-Boc-L-lysine H-Lys(Boc)-OH
  • N6-Boc-L-lysine
CAS:
2418-95-3
MF:
C11H22N2O4
MW:
246.3
Product Categories:
  • Lysine [Lys, K]
  • Amino Acids and Derivatives
  • Amino Acids (N-Protected)
  • Biochemistry
  • Boc-Amino Acids
  • Boc-Amino acid series
  • Amino Acids
Mol File:
2418-95-3.mol
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H-Lys(Boc)-OH Chemical Properties

Melting point:
250 °C (dec.)(lit.)
alpha 
17 º (c=1% in acetic acid)
Boiling point:
389.3°C (rough estimate)
Density 
1.1313 (rough estimate)
refractive index 
18 ° (C=1, AcOH)
storage temp. 
2-8°C
solubility 
Soluble in DMSO
form 
powder to crystal
pka
2.53±0.24(Predicted)
color 
White to Almost white
optical activity
[α]20/D +18°, c = 1 in acetic acid
Water Solubility 
Slightly soluble in water.
BRN 
2417626
InChIKey
VVQIIIAZJXTLRE-QMMMGPOBSA-N
CAS DataBase Reference
2418-95-3(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29241990

MSDS

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H-Lys(Boc)-OH Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

It is used as therapy to treat recurrent herpes simplex infections.

General Description

H-Lys(Boc)-OH, also known as H-Lys(t-BOC)-OH, is an ε-amino-protected lysine. Its e-amino free lysine could be conjugated to polyurethane surfaces by reaction of the alpha-amino group with the NHS and deprotection. The covalent conjugation was carried out in phosphate-buffered saline (PBS), pH 8.2. Lysine was used to create a plasminogen-binding potentially fibrinolytic surface[1].

References

[1] Chen H , et al. Surfaces having dual fibrinolytic and protein resistant properties by immobilization of lysine on polyurethane through a PEG spacer. Journal of Biomedical Materials Research Part A, 2008; 90A: 940-946.

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