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10-[3-(Dimethylamino)propyl]-10H-phenothiazine 5-oxide

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10-[3-(Dimethylamino)propyl]-10H-phenothiazine 5-oxide Basic information

Product Name:
10-[3-(Dimethylamino)propyl]-10H-phenothiazine 5-oxide
Synonyms:
  • Promazine Impurity 1(Promazine EP Impurity A)
  • Promazine 5-sulfoxide
  • Promazine EP Impurity A
  • Promazine sulfoxide
  • Propazine sulfoxide
  • 3-(10H-Phenothiazin-10-yl)-N,N-dime
  • 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, 5-oxide
  • 3-(10H-Phenothiazin-10-yl)- N,N-dimethylpropan-1-amine S-Oxide
CAS:
146-21-4
MF:
C17H20N2OS
MW:
300.42
Mol File:
146-21-4.mol
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10-[3-(Dimethylamino)propyl]-10H-phenothiazine 5-oxide Chemical Properties

Melting point:
114 - 116°C
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form 
Solid
color 
Light Yellow
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10-[3-(Dimethylamino)propyl]-10H-phenothiazine 5-oxide Usage And Synthesis

Uses

Promazine Sulfoxide is a metabolite of Chlorpromazine (C424750) and an impurity of Promazine (P756300). Both Chlorpromazine and Promazine are antipsychotic drugs.

Definition

ChEBI: Promazine sulfoxide is a member of the class of phenothiazines that is promazine carrying an oxo group at position 5. It is a metabolite of the anti-psychotic medication, chlorpromazine. It has a role as a drug metabolite. It is a member of phenothiazines, a sulfoxide and a tertiary amino compound. It is functionally related to a promazine.

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10-[3-(Dimethylamino)propyl]-10H-phenothiazine 5-oxide(146-21-4)Related Product Information