THIOPERAMIDE MALEATE Chemical Properties

storage temp. 

Store at -20°C

solubility 

H₂O: 10 mg/mL

form 

solid

color 

white

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

THIOPERAMIDE MALEATE Usage And Synthesis

Uses

Thioperamide is a highly potent and selective ligand for histamine H3-receptors.

Definition

ChEBI: Thioperamide is a primary aliphatic amine.

Biological Activity

Potent histamine H 3 and H 4 antagonist/inverse agonist. K i values are 25 and 27 nM for human recombinant H 3 and H 4 receptors respectively. Blocks eosinophil shape change (IC 50 = 1.4 μ M) and chemotaxis (IC 50 = 519 nM) induced by histamine. Freely crosses the blood-brain barrier. Also available as part of the Histamine H 3 Receptor Tocriset™ .

storage

Store at -20°C

THIOPERAMIDE MALEATE(106243-16-7)Related Product Information

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• 4-(1H-IMIDAZOLE-4(5)-YL) PIPERIDINE
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• 1-PIPERIDINETHIOCARBOXAMIDE
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