(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Chemical Properties

Boiling point:

463.2±45.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

pka

2.70±0.70(Predicted)

InChI

InChI=1S/C16H16F3NO4/c1-3-24-16(22)10(7-20-8-4-5-8)14(21)9-6-11(17)13(19)15(23-2)12(9)18/h6-8,20H,3-5H2,1-2H3/b10-7-

InChIKey

HVJXUGXNDLCTGC-YFHOEESVSA-N

SMILES

C(=C/NC1CC1)(\C(C1C(F)=C(OC)C(F)=C(F)C=1)=O)/C(=O)OCC

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE Usage And Synthesis

Uses

2-(2,4,5-Trifluoro-3-methoxybenzoyl)-3-cyclopropylaminoacrylic Acid Ethyl Ester is used in the preparation Gatifloxacin (G250000) and key intermediates for the synthesis third-generation fluoroquinolone antibiotics.

(Z)-ETHYL 3-(CYCLOPROPYLAMINO)-2-(2,4,5-TRIFLUORO-3-METHOXYBENZOYL)ACRYLATE(112811-70-8)Related Product Information

• 2,4,5-Trifluoro-3-methoxybenzoyl chloride
• Cyclopropylamine
• Moxifloxacin Ethyl Ester
• 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid ethyl ester
• 6-Benzyl-5,7-dihydro-5,7-dioxopyrrolo[3,4-b]pyridine
• Moxifloxacin Impurity 46
• 1-Cyclopropyl-7-8-difluoro-6-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester
• (4aS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine
• trans-octahydro-1H-pyrrolo[3,4-b]pyridine
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid
• cis-Octahydropyrrolo[3,4-b]pyridine
• N-Methyl Moxifloxacin
• CIS-OCTAHYDROPYRROLO[3,4-B]PYRIDINE
• Moxifloxacin Impurity 29
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-hydroxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid
• Moxifloxacin
• 1-Cyclopropyl-8-ethoxy-6-fluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• Moxifloxacin hydrochloride