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5'-Epi-LaMivudine

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5'-Epi-LaMivudine Basic information

Product Name:
5'-Epi-LaMivudine
Synonyms:
  • 5'-Epi-LaMivudine
  • 2'-Epi-LaMivudine
  • (2S-trans)-4-AMino-1-[2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
  • 4-AMino-1-[(2S,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
  • trans(-)-2-HydroxyMethyl-5-(cytosin-1-yl)-1,3-oxathiolane
  • Lamivudine Impurity 4 (Lamivudine Diastereoisomer)
  • Lamivudine Diastereoisomer
  • Lamivudine 2-Epimer
CAS:
136846-20-3
MF:
C8H11N3O3S
MW:
229.26
Product Categories:
  • Amines, Anti-virals, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • Amines
  • Anti-virals
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
136846-20-3.mol
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5'-Epi-LaMivudine Chemical Properties

Melting point:
172.6 °C(Solv: water (7732-18-5); methanol (67-56-1))
Boiling point:
475.4±55.0 °C(Predicted)
Density 
1.73±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
pka
13.83±0.10(Predicted)
color 
Off-White to Pale Yellow
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5'-Epi-LaMivudine Usage And Synthesis

Uses

2’-Epi-Lamivudine (Lamivudine EP Impurity B) is an epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.

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