Eliglustat Chemical Properties

Melting point:

87-92°C

Boiling point:

615.5±55.0 °C(Predicted)

Density 

1.123±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

13.45±0.20(Predicted)

color 

White to Off-White

Eliglustat Usage And Synthesis

Uses

Eliglustat is a specific and potent inhibitor of glucosylceramide synthase.

Definition

ChEBI: A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltr nsferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.

Biological Activity

Eliglust at is a potent and selctive glucosylceramide synthase inhibitor approved for treatment of type 1 Gaucher disease.

in vivo

Eliglustat(491833-29-5)Related Product Information

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