Basic information Safety Supplier Related

9(10H)-ACRIDONE

Basic information Safety Supplier Related

9(10H)-ACRIDONE Basic information

Product Name:
9(10H)-ACRIDONE
Synonyms:
  • 9-Acridone
  • AURORA KA-3719
  • acridin-9-(10H)-one
  • ACRIDONE, FOR FLUORESCENCE
  • 9,10-Dihydro-9-oxoacridone
  • 9(10H)-Acridone,99%
  • 9(10H)-Acridone,97%
  • 9(10H)-Acridone, pract., 96%
CAS:
578-95-0
MF:
C13H9NO
MW:
195.22
EINECS:
209-434-7
Product Categories:
  • Piperazine derivates
  • Aromatics
  • Heterocycles
  • Fluorescent Labels & Indicators
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
578-95-0.mol
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9(10H)-ACRIDONE Chemical Properties

Melting point:
>300 °C (lit.)
Boiling point:
331.88°C (rough estimate)
Density 
1.1266 (rough estimate)
refractive index 
1.6060 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka
-0.30±0.30(Predicted)
form 
Crystalline Powder
color 
Yellow
Water Solubility 
Insoluble in benzene, chloroform, ether, water and ethanol.
BRN 
7104
InChIKey
FZEYVTFCMJSGMP-UHFFFAOYSA-N
CAS DataBase Reference
578-95-0(CAS DataBase Reference)
NIST Chemistry Reference
9,l0-Dihydro-9-oxoacridine(578-95-0)
EPA Substance Registry System
9(10H)-Acridinone (578-95-0)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36/37/38-22-40
Safety Statements 
22-24/25-37/39-26-36
WGK Germany 
3
RTECS 
AR6976000
TSCA 
Yes
HS Code 
29339900

MSDS

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9(10H)-ACRIDONE Usage And Synthesis

Chemical Properties

YELLOW CRYSTALLINE POWDER

Uses

9(10H)-Acridone is a catabolic product of carbamazepine (C175840) metabolite and can be used as a fluorescent tag for antibody catalysis.

Uses

9(10H)-Acridone is used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate, use for dyeing the organic materials.

Uses

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.

Definition

ChEBI: A member of the class of acridines that is 9,10-dihydroacridine substituted by an oxo group at position 9.

Purification Methods

Dissolve ~1g in ca 1% NaOH (100mL), add 3M HCl to pH 4 when acridone separates as a pale yellow solid with m just above 350o (sharp). It can be recrystallised from large volumes of H2O to give a few mg. It is soluble in 160 parts of boiling EtOH (540 parts at 22o) [Albert & Phillips J Chem Soc 1294 1956]. Afew decigms are best crystallised as the hydrochloride from 400 parts of 10N HCl (90% recovery) from which the free base is obtained by washing the salt with H2O. A small quantity can be recrystallised (as the neutral species) from boiling AcOH. Larger quantities are best recrystallised from a mixture of 5 parts of freshly distilled aniline and 12.5 parts of glacial acetic acid. Acridone distils unchanged at atmospheric pressure, but the boiling point was not recorded, and some sublimation occurs below 350o. It has UV: 399nm. [see max Albert, The Acridines Arnold Press pp 201, 372 1966; for pKa see Kalatzis J Chem Soc (B) 96 1969, Beilstein 23/9 V 7.]

9(10H)-ACRIDONESupplier

Zhengzhou Yuanli Biological Technology Co., Ltd. Gold
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