Basic information Safety Supplier Related

APY29

Basic information Safety Supplier Related

APY29 Basic information

Product Name:
APY29
Synonyms:
  • APY29
  • N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine
  • N2-(1H-benzo[d]imidazol-6-yl)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
  • Reaxys ID: 20097347
  • CS-1412
  • APY 29; APY-29
  • 2,4-Pyrimidinediamine, N2-1H-benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-
  • 2,4-Pyrimidinediamine,N2-1H-benzimidazol-5-yl-N4-(3-cyclopropyl-1H-pyrazol-5-yl)-
CAS:
1216665-49-4
MF:
C17H16N8
MW:
332.36
Mol File:
1216665-49-4.mol
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APY29 Chemical Properties

Melting point:
>280°C (dec.)
Boiling point:
782.3±70.0 °C(Predicted)
Density 
1.559±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
12.93±0.30(Predicted)
form 
Solid
color 
Pale Beige to Light Brown
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APY29 Usage And Synthesis

Uses

APY29 is a modulator of inositol requiring enzyme IRE1α, a protein sited in the endoplasmic recticulum that has kinase and RNase activities triggered by endoplasmic recticulum stress. It also functions in the allosteric control of IRE1α endoribonuclease using kinase inhibitors for the development of drugs for endoplasmic recticulum stress related diseases.

storage

Store at -20°C

APY29Supplier

Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Email
info@chemexpress.com
MedChemexpress LLC
Tel
021-58955995
Email
sales@medchemexpress.cn
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Email
info@adooq.com