AF12198
AF12198 Basic information
- Product Name:
- AF12198
- Synonyms:
-
- AF12198
- AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2
- AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2
- AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2
- L-Leucinamide, N-acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-
- Ac-FEWTPGWYQ（Aze）YALPL-NH2
- AF12198（TFA）
- CAS:
- 185413-30-3
- MF:
- C96H123N19O22
- MW:
- 1895.12
- Mol File:
- 185413-30-3.mol
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AF12198 Chemical Properties
- Melting point:
- >179°C (dec.)
- Density
- 1.353±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
- form
- solid
- pka
- 4.44±0.10(Predicted)
- color
- White to Off-White
MSDS
- Language:English Provider:SigmaAldrich
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AF12198 Usage And Synthesis
Uses
AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.
storage
Store at -20°C
AF12198Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
Creative Peptides
- Tel
- info@creative-peptides.com