Basic information Safety Supplier Related

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

Basic information Safety Supplier Related

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Basic information

Product Name:
5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester
Synonyms:
  • 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester
  • beta-Adrenergic Receptor Kinase 1 Inhibitor
  • 2-Furancarboxylic acid, 5-[2-(5-nitro-2-furanyl)ethenyl]-, methyl ester
  • βARK1 Inhibitor
  • GRK-2 Inhibitor,GRK2 Inhibitor
  • Methyl (E)-5-(2-(5-nitrofuran-2-yl)vinyl)furan-2-carboxylate
  • GRK2 Inhibitor 1
CAS:
24269-96-3
MF:
C12H9NO6
MW:
263.2
Product Categories:
  • Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
24269-96-3.mol
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5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Chemical Properties

Melting point:
139-140 °C
Boiling point:
408.4±45.0 °C(Predicted)
Density 
1.400±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Acetone (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Yellow
Sensitive 
Light Sensitive
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5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Usage And Synthesis

Uses

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.

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