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Intermediate of Rolapitant

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Intermediate of Rolapitant Basic information

Product Name:
Intermediate of Rolapitant
Synonyms:
  • Intermediate of Rolapitant
  • (2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate
  • 3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-
  • 3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID
  • Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate
CAS:
205654-80-4
MF:
C23H19NO4
MW:
373.4
Mol File:
205654-80-4.mol
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Intermediate of Rolapitant Chemical Properties

Boiling point:
591.6±50.0 °C(Predicted)
Density 
1.270±0.06 g/cm3(Predicted)
pka
-3.96±0.60(Predicted)
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Intermediate of Rolapitant Usage And Synthesis

Uses

(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.

Intermediate of RolapitantSupplier

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