Imexon
Imexon Basic information
- Product Name:
- Imexon
- Synonyms:
-
- bm06002
- 4-IMINO-1,3-DIAZABICYCLO-[3.1.0]HEXAN-2-ONE
- imexon
- 4-Amino-1,3-diazabicyclo[3.1.0]hex-3-en-2-one
- AMpliMexon
- Imexon (Amplimexon
- 1,3-Diazabicyclo[3.1.0]hex-3-en-2-one, 4-amino-
- CAS:
- 59643-91-3
- MF:
- C4H5N3O
- MW:
- 111.1
- EINECS:
- 261-838-2
- Mol File:
- 59643-91-3.mol
More
Less
Imexon Chemical Properties
- Boiling point:
- 231.6±23.0 °C(Predicted)
- Density
- 2.26±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- pka
- 4.79±0.20(Predicted)
- form
- Solid
- color
- White to off-white
MSDS
- Language:English Provider:SigmaAldrich
More
Less
Imexon Usage And Synthesis
Uses
Cancer chemotherapy.
brand name
Amplimexon (Amplimed).
in vivo
Imexon (BM 06002) in combination with DTIC results in an increase in the peak plasma imexon level in non-tumor-bearing mice. The combination of both drugs increases plasma imexon AUC by 22% (p=0.026). Imexon (BM 06002) (100 mg/kg/day, i.v.) treatment decreases the body weight of SCID mice bearing human A375 melanoma tumors, but there is no significant difference in tumor growth[2]. Imexon (BM 06002) (100 mg/kg) in combination with GEM shows synergistic inhibition of Panc-1 tumor growth in SCID mice.
ImexonSupplier
LGM Pharma
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
NCE Biomedical Co.,Ltd.
- Tel
- 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
Henan Anky Chemical Technology Co., Ltd.
- Tel
- 17836913271
- 3224305243@qq.com
Zhengzhou JACS Chemical Co., Ltd.
- Tel
- 0371-0371-86259281 15981966935
- jacschem@163.com