TMPYP Chemical Properties

Melting point:

>300℃

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

water: soluble50MM(lit.)

form 

Purple solid

color 

Dark red to Dark purple to Dark blue

Water Solubility 

Soluble to 50 mM in water

BRN 

6049195

Stability:

Hygroscopic, Light Sensitive

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

F 

3-8-10

HS Code 

2933.99.9701

MSDS

• Language:English Provider:SigmaAldrich

TMPYP Usage And Synthesis

Uses

TMPyP4 is a potent inhibitor of telomerase activity.

Definition

ChEBI: An organosulfonate salt that is the tetrakis(p-toluenesulfonate) salt of meso-tetrakis(N-methyl-4-pyridyl)porphine.

General Description

5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p toluenesulfonate) (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent 1O₂ luminescence signals on incubation with the fungus, Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer.

storage

Store at +4°C

TMPYP(36951-72-1)Related Product Information

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