Basic information Safety Supplier Related

XEN907

Basic information Safety Supplier Related

XEN907 Basic information

Product Name:
XEN907
Synonyms:
  • XEN907
  • 1-CYCLOPENTYL-1,2-DIHYDRO-6',10',12'-TRIOXASPIRO[INDOLE-3,4'-TRICYCLO[7.3.0.0^{3,7}]DODECANE]-1',3'(7'),8'-TRIEN-2-ONE
  • XEN907; XEN 907; XEN-907
  • Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-pentyl-
  • 1'-pentylspiro[6H-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one
  • XEN907,XEN-907
  • 1-Pentyl-6'H-spiro[indoline-3,7'-[1,3]dioxolo[4,5-f]benzofuran]-2-one
CAS:
912656-34-9
MF:
C21H21NO4
MW:
351.4
Mol File:
912656-34-9.mol
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XEN907 Chemical Properties

Melting point:
88-90 °C
Boiling point:
566.9±50.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
-0.19±0.20(Predicted)
form 
Solid
color 
White to off-white
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XEN907 Usage And Synthesis

Description

XEN907 is a novel spirooxindole NaV1.7 blocker with IC50 of 3 nM. It shows a further 10-fold increase in potency, which represents a promising structure for further optimization efforts in vitro.

XEN907Supplier

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