XD14
XD14 Basic information
- Product Name:
- XD14
- Synonyms:
-
- XD14
- XD 14;XD-14
- CS-2672
- 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
- XD14,Inhibitor,Epigenetic Reader Domain,XD-14,XD 14,inhibit
- 1H-Pyrrole-2-carboxamide, 4-acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-
- 4-acetyl-N-[5-(diethylsulfamoyl)-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
- XD14, 10 mM in DMSO
- CAS:
- 1370888-71-3
- MF:
- C20H27N3O5S
- MW:
- 421.51
- Mol File:
- 1370888-71-3.mol
More
Less
XD14 Chemical Properties
- Density
- 1.300±0.06 g/cm3(Predicted)
- form
- Solid
- pka
- 7.47±0.50(Predicted)
- color
- Off-white to light yellow
- InChI
- InChI=1S/C20H27N3O5S/c1-6-15-18(13(5)24)12(4)21-19(15)20(26)22-16-11-14(9-10-17(16)25)29(27,28)23(7-2)8-3/h9-11,21,25H,6-8H2,1-5H3,(H,22,26)
- InChIKey
- DPBKLIVPNYGQQG-UHFFFAOYSA-N
- SMILES
- N1C(C)=C(C(C)=O)C(CC)=C1C(NC1=CC(S(N(CC)CC)(=O)=O)=CC=C1O)=O
More
Less
XD14 Usage And Synthesis
Uses
4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide is a bromodomain and extra-terminal (BET) inhibitor and exerts a strong inhibitory potential on the proliferation of specific leukemia cell lines.
IC 50
BRD2: 170 nM (Kd); BRD3: 380 nM (Kd); BRD4: 160 nM (Kd)
XD14Supplier
ChemeGen Gold
- Tel
- 18818260767
- 2625930290@qq.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com