DANSYLAMINO-PITC
DANSYLAMINO-PITC Basic information
- Product Name:
- DANSYLAMINO-PITC
- Synonyms:
-
- DANSYLAMINO-PITC
- DNSAPITC
- 4-[[5-(DIMETHYLAMINO)-1-NAPHTHYLSULFONYL]AMINO]PHENYLISOTHIOCYANATE
- 4-(DANSYLAMINO)PHENYL ISOTHIOCYANATE
- 4-(N-1-DIMETHYLAMINONAPHTHALENE-5-SULFONYLAMINO)PHENYL ISOTHIOCYANATE
- 4-(5-DIMETHYLAMINONAPHTH.-1-SULF.AMINO)&
- DANSYLAMINO-PITC [FLUORESCENT COUPLING REAGENT FOR EDMAN DEGRADATION]
- fluorescentcouplingreagentforedmandegradation]
- CAS:
- 102417-94-7
- MF:
- C19H17N3O2S2
- MW:
- 383.49
- Product Categories:
-
- Fluorescent Labels & Indicators
- Sulfur & Selenium Compounds
- Fluorescent Labels and Indicators
- Mol File:
- 102417-94-7.mol
DANSYLAMINO-PITC Chemical Properties
- Melting point:
- 125-128 °C
- storage temp.
- 2-8°C
- solubility
- Acetonitrile, DMSO, Methanol
- form
- Solid
- color
- Pale Yellow Green
- Stability:
- Light Sensitive; Store at -20°C and Desicate.
MSDS
- Language:English Provider:SigmaAldrich
DANSYLAMINO-PITC Usage And Synthesis
Chemical Properties
Pale Green Solid
Uses
A fluorescent PITC homologue Edman-type reagent with similar coupling efficiency and repetitive degradation yield to those of PITC. Naphthalene derivatives may be particularly useful for preparing fluorescent drug or ligand analogues that are expected to bind to hydrophobic sites in proteins or membranes. The lipophilicity of these reagents may also facilitate the labelling of sites within the membrane-spanning portions of cellular proteins.Fluorescence: max. Abs. l = 335nm, max. Em. l = 536nm (in methanol)
Uses
A fluorescent PITC homologue Edman-type reagent with similar coupling efficiency and repetitive degradation yield to those of PITC, DansylaMino-PITC may be particularly useful for preparing fluorescent drug or ligand analogues that are expected to bind to hydrophobic sites in proteins or membranes. The lipophilicity of these reagents may also facilitate the labelling of sites within the membrane-spanning portions of cellular proteins.
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