Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- Chemical Properties

Density 

1.243±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

4.22±0.40(Predicted)

Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- Usage And Synthesis

Uses

LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM[1].

IC 50

LTB₄: 70 nM (IC₅₀)

References

[1] Hatzelmann A, et al. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. Biochem Pharmacol. 1994 Jun 15;47(12):2259-68. DOI:10.1016/0006-2952(94)90264-x