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10-O-2,2-Dichloroethoxycarbonyl Docetaxe

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10-O-2,2-Dichloroethoxycarbonyl Docetaxe Basic information

Product Name:
10-O-2,2-Dichloroethoxycarbonyl Docetaxe
Synonyms:
  • 10-O-2,2-Dichloroethoxycarbonyl Docetaxe
  • 6-Dichloroethoxy-carbonyl docetaxel
  • Docetaxel Impurity 15
  • 10- Dec Docetaxel
  • Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-6-[[(2,2-dichloroethoxy)carbonyl]oxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
  • Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-6-[[(2,2-dichloroethoxy)carbonyl]oxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4...
  • 10-Dichloroethoxycarbonyl docetaxel
CAS:
158810-73-2
MF:
C46H55Cl2NO16
MW:
948.84
Mol File:
158810-73-2.mol
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10-O-2,2-Dichloroethoxycarbonyl Docetaxe Chemical Properties

Boiling point:
985.9±65.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
11.20±0.46(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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10-O-2,2-Dichloroethoxycarbonyl Docetaxe Usage And Synthesis

Uses

10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an antineoplastic and antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin.Docetaxel Impurity 1.

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