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N-Acetyl-Lys-Octreotide

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N-Acetyl-Lys-Octreotide Basic information

Product Name:
N-Acetyl-Lys-Octreotide
Synonyms:
  • N-Acetyl-Lys-Octreotide
  • Octreotide Impurity 2
  • Acetyl-Lys-octreotide
  • (Lys(Ac)?)-Octreotide acetate salt
  • L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide
  • Lys(Ac)]5-Octreotide (10 mg) (D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2-->7)-disulfide)
  • 800016Q-1
  • (4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(4-acetamidobutyl)-19-((R)-2-amino-3-phenylpropanamido)-16-benzyl-N-((2R,3R)-1,3-dihydroxybutan-2-yl)-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo
CAS:
173606-11-6
MF:
C51H68N10O11S2
MW:
1061.28
EINECS:
253-368-1
Mol File:
173606-11-6.mol
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N-Acetyl-Lys-Octreotide Chemical Properties

Boiling point:
1502.2±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
solubility 
Acetic Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.60±0.70(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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N-Acetyl-Lys-Octreotide Usage And Synthesis

Uses

N-Acetyl-Phe-Octreotide is used as reactant/reagent in inhibition of octreotide acylation inside PLGA microspheres by derivatization of amines of peptide with self-immolative protecting group.

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