ANTI-CLAUDIN-1 Chemical Properties

storage temp. 

-20°C

form 

buffered aqueous solution

biological source

rabbit

Safety Information

WGK Germany 

nwg

Storage Class

10 - Combustible liquids

ANTI-CLAUDIN-1 Usage And Synthesis

Uses

Anti-Claudin-1 antibody produced in rabbit has been used in immunohistochemistry and immunoblotting,

Biological Activity

Claudin-1 is frequently up-regulated in colorectal carcinomas (CRCs), resulting in tumor differentiation and progression. Defects in the gene encoding claudin-1 are the cause of an autosomal recessive syndrome named ichthyosis-sclerosing cholangitis neonatal (NISCH). It participates in the barrier formation of tight junction. It modulates the tight junctions in human airway epithelium. CLDN1 acts as a receptor for the hepatitis C virus entry.