DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE Chemical Properties

Melting point:

158-162°C

storage temp. 

Inert atmosphere,2-8°C

solubility 

DMSO (Slightly), Methanol (Sparingly)

form 

Solid

color 

Off-White to Pale Grey

Water Solubility 

Slightly soluble in water.

Sensitive 

Hygroscopic

BRN 

3597947

InChI

InChI=1S/C10H13NO2.ClH/c1-13-10(12)9(11)7-8-5-3-2-4-6-8;/h2-6,9H,7,11H2,1H3;1H

InChIKey

SWVMLNPDTIFDDY-UHFFFAOYSA-N

SMILES

C1(C=CC=CC=1)CC(N)C(=O)OC.Cl

CAS DataBase Reference

5619-07-8(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

MSDS

• Language:English Provider:ALFA

DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE Usage And Synthesis

Uses

DL-Phenylalanine methyl ester hydrochloride, is an aminoacid which is widely used in pharmaceuticals and foods.

Synthesis

GENERAL METHOD: DL-Phenylalanine (8.16 g, 0.040 mol) was dissolved in methanol (80 mL) and thionyl chloride (SOCl2, 14.28 g, 0.120 mol) was added slowly and dropwise. The reaction mixture was stirred at room temperature for 30 min. Subsequently, the reaction solution was concentrated and the solid product was collected by filtration. The solid residue was washed with acetone and dried under infrared lamp to afford methyl 2-amino-3-phenylpropionate hydrochloride (compound 3a) as a white solid (8.07 g, 92.54% yield). Melting point: 220°C (decomposition), literature value: 221-222°C.

References

[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 21, p. 6466 - 6476

DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE(5619-07-8)Related Product Information

• 4-CHLORO-DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE,P-CHLORO-DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE
• 2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID
• H-DL-Phe(4-NO2)-OMe.HCl
• 4-BROMO-DL-PHENYLALANINE
• H-DL-PHE-OTBU HCL
• 2-AMINO-3-P-TOLYL-PROPIONIC ACID
• 4-Iodo-DL-phenylalanine
• H-DL-Phe(4-CH2COOtBu)-OH
• P-AMINO-DL-PHENYLALANINE
• (2S)-2-amino-3-(4-cyclohexylphenyl)propanoic acid
• 2-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID
• DL-2-(2-Chlorophenyl)glycine
• H-DL-Phe(2-Me)-OH
• H-DL-Phe-PNA.HCl
• H-DL-Phe(3-Me)-OH
• H-DL-Phe(4-NO2)-OEt.HCl
• 4-NITRO-DL-PHENYLALANINE
• 3-Cyanophenylalanine