2-[2-(4-(2-METHOXYPHENYL)PIPERAZIN-1-YL)ETHYL]-4,4-DIMETHYL-1,3-(2H,4H)-ISOQUINOLINDIONE DIHYDROCHLORIDE Chemical Properties

storage temp. 

Store at RT

solubility 

H2O: >5mg/mL

form 

powder

color 

white to off-white

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

22-50/53

Safety Statements 

60-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

2-[2-(4-(2-METHOXYPHENYL)PIPERAZIN-1-YL)ETHYL]-4,4-DIMETHYL-1,3-(2H,4H)-ISOQUINOLINDIONE DIHYDROCHLORIDE Usage And Synthesis

Uses

ARC 239 dihydrochloride is a selective α2B-AR adrenoreceptor antagonist.

Biological Activity

Selective α 2B adrenoceptor antagonist (pK D values are 8.8, 6.7 and 6.4 at α 2B , α 2A , and α 2D receptors respectively). Also available as part of the α 2 -Adrenoceptor Tocriset™ .

2-[2-(4-(2-METHOXYPHENYL)PIPERAZIN-1-YL)ETHYL]-4,4-DIMETHYL-1,3-(2H,4H)-ISOQUINOLINDIONE DIHYDROCHLORIDE(67339-62-2)Related Product Information

• 1-(2-Methoxyphenyl)piperazine hydrochloride
• 4,4-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE
• 2-[2-(4-(2-METHOXYPHENYL)PIPERAZIN-1-YL)ETHYL]-4,4-DIMETHYL-1,3-(2H,4H)-ISOQUINOLINDIONE DIHYDROCHLORIDE
• 4-METHYL-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE