HIPPEASTRINE HYDROBROMIDE Usage And Synthesis

Description

Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.

Uses

Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25?μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities[1].

Definition

ChEBI: Hippeastrine is an indole alkaloid isolated from the Amaryllidaceae family and has been shown to exhibit cytotoxic activity. It has a role as an antineoplastic agent and a metabolite. It is an indole alkaloid, a delta-lactone, a secondary alcohol and an organic heteropentacyclic compound.

References

[1] Chen GL, et al. Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Sci Rep. 2016;6:38284. Published 2016 Dec 6. DOI:10.1038/srep38284

HIPPEASTRINE HYDROBROMIDE(22352-41-6)Related Product Information

• 2-(1-CYCLOHEXENYL)ETHYLAMINE
• cis-3-Hexenyl benzoate
• Piperonylic acid
• 1-(3,4-Methylenedioxyphenyl)-2-butanamine
• N-Methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine
• methyl 4-methoxy-2-methylbenzoate
• 2-(3-METHYL-3-BUTENYL)BENZOIC ACID
• 2-Methyl-4-(2-methylphenyl)but-1-ene
• 5-METHOXY-2-METHYL-BENZOIC ACID METHYL ESTER
• 4-(2-CARBOETHOXYPHENYL)-1-BUTENE
• (R)-1-(3, 4-METHYLENEDIOXYPHENYL)-2-PROPANOL
• 4-(3-METHOXYPHENYL)-2-METHYL-1-BUTENE
• 6-METHOXY-ISOCHROMAN
• 2-(3-BUTENYL)BENZOIC ACID
• 6-METHYL-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE
• 4-(4-METHOXYPHENYL)-2-METHYL-1-BUTENE
• methyl 1,3-benzodioxole-5-carboxylate
• UNGERINE NITRATE