HIPPEASTRINE HYDROBROMIDE
- Product Name
- HIPPEASTRINE HYDROBROMIDE
- CAS No.
- 22352-41-6
- Chemical Name
- HIPPEASTRINE HYDROBROMIDE
- Synonyms
- HIPPEASTRINE HBr;(+)-Hippeastrine HBr;HIPPEASTRINE HYDROBROMIDE
- CBNumber
- CB5436572
- Molecular Formula
- C17H18BrNO5
- Formula Weight
- 396.24
- MOL File
- 22352-41-6.mol
HIPPEASTRINE HYDROBROMIDE Chemical Properties,Usage,Production
Description
Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.
Uses
Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25?μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities[1].
Definition
ChEBI: Hippeastrine is an indole alkaloid isolated from the Amaryllidaceae family and has been shown to exhibit cytotoxic activity. It has a role as an antineoplastic agent and a metabolite. It is an indole alkaloid, a delta-lactone, a secondary alcohol and an organic heteropentacyclic compound.
References
[1] Chen GL, et al. Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Sci Rep. 2016;6:38284. Published 2016 Dec 6. DOI:10.1038/srep38284
HIPPEASTRINE HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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