MAG-FURA-2, AM
MAG-FURA-2, AM Basic information
- Product Name:
- MAG-FURA-2, AM
- Synonyms:
-
- Fura 2-AM magnesium-selective analog
- MAFENIDEACETATE
- FURA 2-AM magnesium selective analogue
- 2-[5-[2-(acetoxymethoxy)-2-keto-ethoxy]-6-[bis[2-(acetoxymethoxy)-2-keto-ethyl]amino]benzofuran-2-yl]oxazole-5-carboxylic acid acetoxymethyl ester
- acetyloxymethyl 2-[5-[2-(acetyloxymethoxy)-2-oxo-ethoxy]-6-[bis[2-(acetyloxymethoxy)-2-oxo-ethyl]amino]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
- acetyloxymethyl 2-[5-[2-(acetyloxymethoxy)-2-oxoethoxy]-6-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
- Mag-Fura 2, AM Cell PerMeant
- Furaptra, AM ester [Known as Mag-Fura-2, AM ester, TM of Molecular Probes]
- CAS:
- 130100-20-8
- MF:
- C30H30N2O19
- MW:
- 722.56
- Product Categories:
-
- Benzofuran
- Mol File:
- 130100-20-8.mol
MAG-FURA-2, AM Chemical Properties
- Melting point:
- >200℃
- Boiling point:
- 797.5±70.0 °C(Predicted)
- Density
- 1.436±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Insoluble in water; soluble in dimethyl sulfoxide, ethyl acetate
- pka
- -2.19±0.10(Predicted)
- form
- powder
- color
- Light yellow
- Appearance
- Solid Powder
- λmax
- 366 nm
- Biological Applications
- Magnesium indicator; calcium indicator; zinc indicator
MAG-FURA-2, AM Usage And Synthesis
Description
Mag-fura-2 AM is a membrane-permeant, short-wavelength fluorescent indicator for intracellular magnesium. It can be loaded into cells via incubation, and hydrolyzed to mag-fura-2. Intracellular magnesium concentration can be measured by ratio of fluorescence intensity generated by mag-fura-2.
Uses
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions[1].
storage
Store at -20°C
References
[1] García-Martín E, et, al. Intrasynaptosomal free Mg2+ concentration measured with the fluorescent indicator mag-fura-2: modulation by Na+ gradient and by extrasynaptosomal ATP. J Neurochem. 1995 Dec;65(6):2757-64. DOI:10.1046/j.1471-4159.1995.65062757.x
Excitation / Emission Maximum
537 nm/559 ±5 nm
MAG-FURA-2, AMSupplier
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MAG-FURA-2, AM(130100-20-8)Related Product Information
- FURA-2FF
- Rhod-2, tripotassium salt
- fura red
- Quest Rhod-4, AM
- Fura-8, AM
- FURA 2 MAGNESIUM-SELECTIVE ANALOG TETRAPOTASSIUM SALT
- Mag-Fluo-4 potassium salt
- Fura-8FF, AM
- RHOD-FF, AM
- RHOD-2, TRISODIUM SALT
- Indo-1, pentapotassium salt *CAS 132319-21-9*
- MAG-INDO 1-AM
- Fura-8, pentapotassium salt
- Quest Rhod-4, potassium salt
- 1-[2-(5-CARBOXYOXAZOL-2-YL)-6-AMINOBENZOFURAN-5-OXY]-2-(2'-AMINO-5'-METHYLPHENOXY)-ETHANE-N,N,N',N'-TETRAACETIC ACID, 5NA
- MAG-FLUO-4, AM
- RHOD-FF, TRIPOTASSIUM SALT
- RHOD-5N, TRIPOTASSIUM SALT