TH34
TH34 Basic information
- Product Name:
- TH34
- Synonyms:
-
- TH34
- CS-2858
- TH34;TH 34
- 3-(Benzylamino)-N-hydroxy-4-methylbenzamide
- TH34,inhibit,Inhibitor,TH 34,TH-34,HDAC,Histone deacetylases
- Benzamide, N-hydroxy-4-methyl-3-[(phenylmethyl)amino]-
- TH34, 10 mM in DMSO
- CAS:
- 2196203-96-8
- MF:
- C15H16N2O2
- MW:
- 256.3
- Mol File:
- 2196203-96-8.mol
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TH34 Chemical Properties
- Density
- 1.236±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO : 150 mg/mL (585.25 mM)
- pka
- 9.04±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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TH34 Usage And Synthesis
Biological Activity
TH34 is an HDAC6/8/10 inhibitor with IC50 values of 4.6 μM, 1.9 μM and 7.7 μM, respectively, showing high selectivity compared with HDAC1/2/3.
in vitro
TH34 induces caspase-dependent programmed cell death and cell cycle arrest in neuroblastoma cells.
target
| HDAC6 4.6 μM (IC 50 ) | HDAC8 1.9 μM (IC 50 ) | HDAC10 7.7 μM (IC 50 ) |
TH34Supplier
Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel
- 400-6206333 1316706386
- anhua.mao@aladdin-e.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
YouCoChem (Beijing) Chemical Technology Co., Ltd.
- Tel
- 18800159827
- youcochem@163.com
Shanghai Beckham Medical Technology Co., Ltd
- Tel
- 021-13816613772 13816613772
- huahero21@sina.com
BOC Sciences
- Tel
- 16314854226
- info@bocsci.com