AT6
AT6 Basic information
- Product Name:
- AT6
- Synonyms:
-
- AT6
- (2S,4R)-1-[(2R)-3-({2-[2-(2-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,?]trideca-2(6),4,7,10,12-pentaen-9-yl]acetamido}ethoxy)ethoxy]ethyl}sulfanyl)-2-acetamido-3-methylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CAS:
- 2098836-50-9
- MF:
- C48H58ClN9O7S3
- MW:
- 1004.68
- Mol File:
- 2098836-50-9.mol
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AT6 Chemical Properties
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C, protect from light, stored under nitrogen
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 14.05±0.40(Predicted)
- color
- White to off-white
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AT6 Usage And Synthesis
Uses
AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4).
References
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329
AT6Supplier
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Shanghai finete Pharmaceutical Co., Ltd.
- Tel
- 021-021-00000000 18221039705
- finetechpharm@126.com
Jilin Province Woda Biotechnology Co., Ltd.
- Tel
- 13504435624
- 1927928688@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com