NO-1886
NO-1886 Basic information
- Product Name:
- NO-1886
- Synonyms:
-
- Ibrolipim NO-1886
- OPF 009
- Lipoprotein Lipase Activator
- N-(4-bromo-2-cyanophenyl)-4-(diethoxyphosphorylmethyl)benzamide
- NO-1886
- Diethyl 4-[(4-bromo-2-cyanophenyl)carbamoyl]benzylphosphonate
- 4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide
- ibrolipim
- CAS:
- 133208-93-2
- MF:
- C19H20BrN2O4P
- MW:
- 451.25
- Mol File:
- 133208-93-2.mol
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NO-1886 Chemical Properties
- Melting point:
- 160.5-162.1 °C
- Boiling point:
- 512.5±50.0 °C(Predicted)
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- pka
- 11.51±0.70(Predicted)
- color
- off-white to pale yellow
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Safety Information
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-25
- Safety Statements
- 26-36-45
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
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NO-1886 Usage And Synthesis
Uses
Antiatherogenic; antiobesity; antidyslipidemia; anticachexia; and antidiabetes/syndrome.
Uses
Lipoprotein Lipase Activator is an inducer of lipoprotein lipase mRNA.
Biological Activity
Lipoprotein lipase activator. Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis. Long-term administration of NO-1886 protects against the development of experimental atherosclerosis in animals.
NO-1886Supplier
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 17754423994 17754423994
- 2853530910@QQ.com
Beijing Solarbio Science & Tecnology Co., Ltd.
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn