KAZUSAMYCIN A FROM STREPTOMYCES SP.
KAZUSAMYCIN A FROM STREPTOMYCES SP. Basic information
- Product Name:
- KAZUSAMYCIN A FROM STREPTOMYCES SP.
- Synonyms:
-
- KAZUSAMYCIN A FROM STREPTOMYCES SP.
- antibiotic81-484
- antibioticcl1957b
- kazusamycin
- kazusamycina
- 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-2,10,12,16,18-nonadecapentenoic acid
- PD-114721
- 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,10E,12E,16Z,18E)-
- CAS:
- 92090-94-3
- MF:
- C33H48O7
- MW:
- 556.73
- Mol File:
- 92090-94-3.mol
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KAZUSAMYCIN A FROM STREPTOMYCES SP. Chemical Properties
- Boiling point:
- 761.5±60.0 °C(Predicted)
- Density
- 1.109±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- methanol/water: 7:3, soluble
- form
- aqueous methanol solution
- pka
- 5.10±0.33(Predicted)
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Safety Information
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 1
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KAZUSAMYCIN A FROM STREPTOMYCES SP. Usage And Synthesis
Uses
Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity.
Uses
Kazusamycin A is a potent antibiotic shown to induce G2 cell cycle arrest and delay M phase.
KAZUSAMYCIN A FROM STREPTOMYCES SP.Supplier
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Lynnchem
- Tel
- 86-(0)29-85992781 17792393971
- info@lynnchem.com
Novachemistry
- Tel
- 44-20819178-90 02081917890
- info@novachemistry.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel
- +86-400-002-6226 13028896684
- sales@rrkchem.com
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KAZUSAMYCIN A FROM STREPTOMYCES SP.(92090-94-3)Related Product Information
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- KAZUSAMYCIN A FROM STREPTOMYCES SP.