Basic information Safety Supplier Related

CHARTREUSIN

Basic information Safety Supplier Related

CHARTREUSIN Basic information

Product Name:
CHARTREUSIN
Synonyms:
  • CHARTREUSIN
  • antibioticx-465a
  • nsc5159
  • u-7257
  • chartreusin from streptomyces*chartreusis
  • LAMBDAMYCIN
  • 10-[[6-Deoxy-2-O-(6-deoxy-3-O-methyl-α-D-galactopyranosyl)-β-D-galactopyranosyl]oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione
  • LaMbdaMycin, NSC 5159, 747, 1293, X465A, G 261A
CAS:
6377-18-0
MF:
C32H32O14
MW:
640.59
Product Categories:
  • Antibiotic
Mol File:
6377-18-0.mol
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CHARTREUSIN Chemical Properties

Melting point:
185℃
alpha 
D25 +132.5° (c = 0.2 in pyridine); D25 -33° (c = 0.3 in glacial acetic acid)
Boiling point:
592.39°C (rough estimate)
Density 
1.3027 (rough estimate)
refractive index 
1.6130 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly)
form 
Yellow solid.
pka
6?+-.0.20(Predicted)
color 
Light Yellow to Yellow
Water Solubility 
15mg/L(25 ºC)
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-36/37/39-45
HS Code 
29419000
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CHARTREUSIN Usage And Synthesis

Uses

Chartreusin is an antiproliferative agent that inhibits topoisomerase II.

Uses

Chartreusin is an antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

Uses

Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

Definition

ChEBI: Chartreusin is a glycoside and a benzochromenone.

CHARTREUSINSupplier

Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Email
sales@chemwish.com
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Email
sales@sinch.com.cn
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Email
market@aladdin-e.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
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