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(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride

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(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Basic information

Product Name:
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
Synonyms:
  • (R)-1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride
  • (R)-1-(7,8-dihydrophthalen-1-yl)ethan-1-amine hydrochloride
  • (R)-<1-(1-Naphthyl)ethyl>ammonium chloride
  • ?-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
  • (R)-(+)-1-(1-Naphthyl)ethylamine Hcl
  • (R)-(+)-1,1-Naphthyl ethylamine HCI
  • (R)-1-(naphthalen-1-yl)ethanaMine (Hydrochloride)
  • 1-Naphthalenemethanamine, alpha-methyl-, hydrochloride, (alphaR)-
CAS:
82572-04-1
MF:
C12H14ClN
MW:
207.69926
EINECS:
617-358-4
Product Categories:
  • Miscellaneous
  • Amine Salts
  • Chiral Building Blocks
  • Organic Building Blocks
Mol File:
82572-04-1.mol
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(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Chemical Properties

Melting point:
253-257 °C(lit.)
storage temp. 
Sealed in dry,Room Temperature
optical activity
[α]/D 5.2±2°, c = 1 in methanol
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-36/37/38-50
Safety Statements 
26-60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
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(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride Usage And Synthesis

Uses

(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is a pharmaceutical intermediate used in the preparation of cinacalcet hydrochloride, which treats secondary hyperparathyroidism due to chronic kidney disease. In addition, (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is also used in analytical assays. Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.

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