9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Basic information
- Product Name:
- 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
- Synonyms:
-
- 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
- Tacrine HCl hydrate
- Cholinesterase (ChE),inhibit,Tacrine hydrochloride (hydrate),Inhibitor
- Tacrine hydrochloride (hydrate), 10 mM in DMSO
- 1,2,3,4-Tetrahydroacridin-9-amine xhydrochloride xhydrate , Tacrine hydrochloride (hydrate)
- 1,2,3,4-Tetrahydroacridin-9-amine xhydrochloride xhydrate
- CAS:
- 206658-92-6
- MF:
- C13H17ClN2O
- MW:
- 252.74
- Product Categories:
-
- Inhibitors
- Mol File:
- Mol File
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Chemical Properties
- Melting point:
- 284-286°C (lit.)
- storage temp.
- Store at -20°C
- solubility
- H2O: soluble
- form
- powder
- color
- faint yellow
- Water Solubility
- H2O: soluble
- InChI
- 1S/C13H14N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H;1H2
- InChIKey
- PXGRMZYJAOQPNZ-UHFFFAOYSA-N
- SMILES
- O.Cl.Nc1c2CCCCc2nc3ccccc13
Safety Information
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38-40
- Safety Statements
- 22-24/25-26-36/37/39
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- HS Code
- 2933998090
- Storage Class
- 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects - Hazard Classifications
- Acute Tox. 3 Oral
Carc. 2
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Usage And Synthesis
Uses
9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate is a well-known cholinesterase inhibitor commonly used in pharmacological studies.
in vivo
Pretreatment with Tacrine hydrochloride (hydrate) also modifies absolute levels of cocaine self-administration during reacquisition. Body weight declines approximately one-half percent over four days of treatment with intravenous Tacrine hydrochloride (hydrate). Delivery of Tacrine hydrochloride (hydrate) by osmotic pump does not alter either linear- or repeated- cocaine-induced locomotor activity. There is no significant main effect or interaction with Tacrine hydrochloride (hydrate) treatment on active lever responding during reinstatement. Post hoc comparisons indicate that rats self-administering cocaine has significantly lower alkaline phosphatase levels, relative to TTacrine hydrochloride (hydrate)- but not saline- treated rats evaluated by conditioned-place preference[2].
IC 50
AChE; BChE
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%Supplier
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