Basic information Safety Supplier Related

9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%

Basic information Safety Supplier Related

9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Basic information

Product Name:
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
Synonyms:
  • 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
  • Tacrine HCl hydrate
  • Cholinesterase (ChE),inhibit,Tacrine hydrochloride (hydrate),Inhibitor
  • Tacrine hydrochloride (hydrate), 10 mM in DMSO
  • 1,2,3,4-Tetrahydroacridin-9-amine xhydrochloride xhydrate , Tacrine hydrochloride (hydrate)
  • 1,2,3,4-Tetrahydroacridin-9-amine xhydrochloride xhydrate
CAS:
206658-92-6
MF:
C13H17ClN2O
MW:
252.74
Product Categories:
  • Inhibitors
Mol File:
Mol File
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9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Chemical Properties

Melting point:
284-286°C (lit.)
storage temp. 
Store at -20°C
solubility 
H2O: soluble
form 
powder
color 
faint yellow
Water Solubility 
H2O: soluble
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Safety Information

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38-40
Safety Statements 
22-24/25-26-36/37/39
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
2933998090
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9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+% Usage And Synthesis

Uses

9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate is a well-known cholinesterase inhibitor commonly used in pharmacological studies.

in vivo

Pretreatment with Tacrine hydrochloride (hydrate) also modifies absolute levels of cocaine self-administration during reacquisition. Body weight declines approximately one-half percent over four days of treatment with intravenous Tacrine hydrochloride (hydrate). Delivery of Tacrine hydrochloride (hydrate) by osmotic pump does not alter either linear- or repeated- cocaine-induced locomotor activity. There is no significant main effect or interaction with Tacrine hydrochloride (hydrate) treatment on active lever responding during reinstatement. Post hoc comparisons indicate that rats self-administering cocaine has significantly lower alkaline phosphatase levels, relative to TTacrine hydrochloride (hydrate)- but not saline- treated rats evaluated by conditioned-place preference[2].

IC 50

AChE; BChE

9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%Supplier

Sigma-Aldrich
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021-61415566 800-8193336
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Target molecule Corp.
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%(206658-92-6)Related Product Information