PFKP antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Monkey

Background

Phosphofructokinase catalyzes the phosphorylation of fructose-6-phosphate in glycolysis. There are three isozymes: muscle-type, liver-type, and platelet-type. Platelet-type phosphofructokinase is expressed in various cell types. Research studies have shown that genetic variations in PFKP are associated with individuals born small for gestational age that are prone to obesity and diabetes later in adulthood.

References

[1] Mediavilla, D. et al. (2008) J Biochem 144, 235-44.
[2] Eto, K. et al. (1994) Biochem Biophys Res Commun 198, 990-8.
[3] Hannemann, A. et al. (2005) Gene 345, 237-47.
[4] Morrison, N. et al. (1992) Hum Genet 89, 105-6.
[5] Vora, S. (1983) Isozymes Curr Top Biol Med Res 11, 3-23.
[6] Morgan, A.R. et al. (2010) BMC Med Genet 11, 125.

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