FUREGRELATE
FUREGRELATE Basic information
- Product Name:
- FUREGRELATE
- Synonyms:
-
- FUREGRELATE
- 2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-
- Furegarelatum
- Furegarelatum [latin]
- Furegrelate [inn]
- Furegrelato
- Furegrelato [spanish]
- Unii-kx4D9bza6x
- CAS:
- 85666-24-6
- MF:
- C15H11NO3
- MW:
- 253.25
- Mol File:
- 85666-24-6.mol
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FUREGRELATE Chemical Properties
- Boiling point:
- 458.7±35.0 °C(Predicted)
- Density
- 1.322±0.06 g/cm3(Predicted)
- pka
- 3.07±0.30(Predicted)
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FUREGRELATE Usage And Synthesis
Uses
Inhibitor (thromboxane synthetase).
Definition
ChEBI: 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid is a member of benzofurans.
in vivo
Furegrelate (1-5 mg/kg; po) prevents blockage of the coronary artery[1].
Furegrelate (0.1-5 mg/kg; i.v.) prevents the blockage of stenosed coronary arteries caused platelet aggregation[1].
Furegrelate blunts the development of hypoxia-induced pulmonary arterial hypertension (PAH) in an established neonatal piglet model primarily by preserving the structural integrity of the pulmonary vasculature[2].
Furegrelate has a long half-life compared to several other drugs used to treat PAH, including nitric oxide and prostagcyclin analogues; And Furegrelate is highly specific to the target enzyme[2].
FUREGRELATESupplier
Shanghai Synchem Pharma Co., ltd
- Tel
- 21-619849051-1 18521059765
- synchempharma@aliyun.com
Shanghai RenYue Chemical Technology Co., Ltd.
- Tel
- 021-62219190; 18321139117
- 316441092@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com
Taizhou GreenChem Pharma-Tech Co.,Ltd
- Tel
- 15366892466
- greenchem@tzglmk.com