Clopidogrel hydrogen sulfate Chemical Properties

Melting point:

184°C

alpha 

D20 +55.10° (c = 1.891 in methanol)

storage temp. 

2-8°C

solubility 

DMSO: ~26mg/mL

form 

White powder

color 

white

InChIKey

FDEODCTUSIWGLK-RSAXXLAASA-N

CAS DataBase Reference

135046-48-9(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HazardClass 

IRRITANT

Clopidogrel hydrogen sulfate Usage And Synthesis

Anti-platelet aggregation drug

Thrombosis caused by arterial atheromatous plaque leads to acute thrombosis cardiovascular and cerebrovascular events. In this pathogenesis, platelets play a central role, which has been fully studied.
Clopidogrel hydrogen sulfate is similar to ticlopidine, which is a new anti-platelet aggregation drug, successfully developed by French Sanofi-Synthelabo Fort for the prevention and treatment of heart, brain and other arterial circulation disorders caused by the high blood platelet aggregation, such as recent onset of stroke, myocardial infarction and patients diagnosed with peripheral arterial disease. Many countries have already used it, including United States, Europe and China. This product inhibited platelet activation by inhibiting adenosine diphosphate (ADP) pathway to inhibit platelet aggregation. Since clopidogrel hydrogen sulfate takes several days to achieve effective blood concentration, it does not apply to emergency treatment. Stop using 7 to 10 days, platelet function returned to normal state.
The above information is edited by the chemicalbook of Kui Ming.

Chemical Properties

Colorless to light yellow liqui

Uses

Used as an antithrombotic

Uses

rac-Clopidogrel Hydrogen Sulfate is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.

Biochem/physiol Actions

Inhibits ADP-induced platelet aggregation; anti-thrombotic drug.

Clopidogrel hydrogen sulfate(135046-48-9)Related Product Information

• Methyl cyanoacetate
• Ammonium sulfate
• Methyl salicylate
• Pyridine
• Dimethyl sulfate
• Methyl acetate
• Methyl isobutyrylacetate
• Magnesium sulfate heptahydrate
• Methyl bromoacetate
• Clopidogrel
• Tribenuron methyl
• Kresoxim-methyl
• Barium sulfate
• Sodium sulfate
• Clopidogrel Bisulfate
• Thiophanate-methyl
• METSULFURON METHYL
• Methyl phenoxyacetate