Methyl phenoxyacetate Chemical Properties

Melting point:

245 °C

Boiling point:

243 °C (lit.)

Density 

1.149 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.514(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

color 

Colorless to Light orange to Yellow

Specific Gravity

1.149

InChIKey

BZCKRPHEZOHHBK-UHFFFAOYSA-N

LogP

1.410

CAS DataBase Reference

2065-23-8(CAS DataBase Reference)

NIST Chemistry Reference

Acetic acid, phenoxy-, methyl ester(2065-23-8)

EPA Substance Registry System

Acetic acid, phenoxy-, methyl ester (2065-23-8)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

TSCA 

T

HS Code 

29189900

MSDS

• Language:English Provider:Methyl phenoxyacetate
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Methyl phenoxyacetate Usage And Synthesis

Chemical Properties

Methyl phenoxyacetate, when the temperature ≥ 30°C is a clear colorless to slightly yellow liquid; at < 30°C is a white solid. It can be used as disinfectant or pharmaceutical intermediate or pesticide intermediate.

Uses

Methyl phenoxyacetate (MPOA) was used as an acylating agent in the synthesis of loracarbef, a carbacephalosporin antibiotic.

Preparation

synthesis of methyl phenoxyacetate: methyl bromoacetate (10 mL, 105.6 mmol) and phenol (9.9380 g, 105.6 mmol) were dissolved in 250 mL of acetone; K2CO3 (21.89 g, 158 mmol) and KI (5 g, 30 mmol) were added and the mixture heated to reflux with stirring overnight. The mixture was filtered and the resultant solution concentrated in vacuo. Deionized water (200 mL) was added. The reaction mixture was extracted with 50 mL ethyl acetate three times. The combined ethyl acetate layers were washed with brine, dried over MgSO4, and filtered. All ethyl acetate was removed in vacuo, resulting in a slightly yellow liquid (80% yield).

Methyl phenoxyacetate(2065-23-8)Related Product Information

• Methyl glycolate
• Methyl bromoacetate
• Kresoxim-methyl
• Phenoxyacetic acid
• Methyl acrylate
• Methyl acetate
• Methyl cyanoacetate
• Methyl methoxyacetate
• Methylparaben
• Thiophanate-methyl
• Methyl phenylacetate
• Bensulfuron methyl
• METSULFURON METHYL
• Methyl
• Methyl bromide
• Parathion-methyl
• Bis(2,4,6-trichlorophenyl)ethanedioate
• lifibrate