Methyl glycolate Chemical Properties

Melting point:

149-151 °C

Boiling point:

149-151 °C(lit.)

Density 

1.167 g/mL at 25 °C(lit.)

vapor density 

3.12 (vs air)

vapor pressure 

17 mm Hg ( 52 °C)

refractive index 

n20/D 1.417(lit.)

Flash point:

153 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol

pka

13.00±0.10(Predicted)

form 

Liquid

color 

Clear colorless

Water Solubility 

Miscible with water.

BRN 

1699571

InChIKey

GSJFXBNYJCXDGI-UHFFFAOYSA-N

CAS DataBase Reference

96-35-5(CAS DataBase Reference)

NIST Chemistry Reference

Acetic acid, hydroxy-, methyl ester(96-35-5)

EPA Substance Registry System

Acetic acid, hydroxy-, methyl ester (96-35-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

29181990

MSDS

• Language:English Provider:Methyl hydroxyacetate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Methyl glycolate Usage And Synthesis

Chemical Properties

Clear colorless liquid

Uses

Methyl glycolate is a chemical reagent used in the synthesis of taxol and rapamycin. It is used in leather tanning and textile dyeing. It acts as a flavoring agent, preservative in food processing, in water treatment industries and as chemical intermediates. Further, it is used in emulsion polymers, ink and paint additive to improve flow properties and impart gloss. It plays an important role in producing triisopropylsilanyloxy-acetic acid methyl ester using imidazole as reagent.

Reactions

Methyl glycolate possesses chemical properties similar to both alcohols and esters, and can undergo carbonylation, hydrolysis, and oxidation reactions.

General Description

Synthesis of methyl glycolate from the carbonylation of HCHO using heteropoly acids (HPAs) as catalysts, followed by esterification with methanol was reported. Size-selective vibrational spectroscopy of methyl glycolate clusters was reported.

Synthesis

Methyl glycolate was synthesized in a single step by reaction of CA with sodium hydroxide and methanol in an autoclave reactor. The highest MG yield of 81.4% was obtained under suitable conditions of 8:1:1 methanol: sodium hydroxide: CA (molar ratio), after 5 h at 150 °C, in a laboratory autoclave reactor.

Methyl glycolate(96-35-5)Related Product Information

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• FATTY ACID METHYL ESTER MIX C8-C22
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